ABMM無料問題集「American Society of Microbiology ABMM」

質問 1

A microbiology laboratory is processing a throat swab for the detection of Group A Streptococcus. Culture on sheep blood agar reveals beta-hemolytic colonies. Which of the following tests can be used to presumptively identify Streptococcus pyogenes?

（A）Bile esculin hydrolysis

（B）Coagulase test

（C）Bacitracin susceptibility

（D）Catalase test

正解：C 解答を投票する

質問 2

A microbiology laboratory is performing Gram staining on a bacterial smear. If the safranin counterstain is omitted, Gram-negative bacteria will appear:

（A）Colorless

（B）Purple

（C）Brown

（D）Blue

正解：A 解答を投票する

質問 3

A clinical microbiology laboratory is using a nucleic acid amplification test (NAAT) to detect Mycobacterium tuberculosis directly from sputum. A positive result indicates:

（A）The presence of M. tuberculosis DNA, which could be from viable or non-viable organisms.

（B）Drug susceptibility information for the M. tuberculosis strain.

（C）The presence of viable M. tuberculosis organisms.

（D）Active tuberculosis disease requiring immediate treatment.

正解：A 解答を投票する

質問 4

A research team is investigating the development of a novel vaccine against influenza virus. They are focusing on conserved epitopes within the hemagglutinin (HA) and neuraminidase (NA) proteins to elicit broadly neutralizing antibodies. Which of the following approaches is MOST likely to achieve this goal?

（A）Developing a live-attenuated influenza vaccine containing multiple serotypes.

（B）Designing a subunit vaccine that presents highly variable regions of HA and NA.

（C）Administering high doses of inactivated influenza vaccine annually.

（D）Utilizing a recombinant viral vector to deliver conserved epitopes of HA and NA.

正解：D 解答を投票する

質問 5

Transmissible spongiform encephalopathies (TSEs), such as Creutzfeldt-Jakob disease (CJD) in humans and Bovine Spongiform Encephalopathy (BSE) in cattle, are caused by infectious agents composed primarily of:

（A）Viroids (small, circular RNA molecules)

（B）Slow-growing bacteria lacking a cell wall

（C）Defective viral particles requiring a helper virus

（D）Aberrantly folded host-encoded prion proteins (PrP<sup>Sc</sup>)

正解：D 解答を投票する

質問 6

A patient with a history of travel to a developing country presents with chronic diarrhea, abdominal pain, and weight loss. Stool examination reveals the presence of cysts containing four nuclei and chromatoidal bars with rounded ends. The MOST likely causative organism is:

（A）Entamoeba histolytica

（B）Cyclospora cayetanensis

（C）Cryptosporidium parvum

（D）Giardia lamblia

正解：A 解答を投票する

質問 7

A key virulence factor of Neisseria meningitidis that plays a major role in immune evasion and is the target for serogrouping is the:

（A）Polysaccharide capsule

（B）Lipooligosaccharide (LOS) endotoxin

（C）Pili

（D）IgA protease

正解：A 解答を投票する

質問 8

An elderly patient in a long-term care facility develops a localized outbreak of painful vesicles along a dermatome. Tzanck smear of a vesicle reveals multinucleated giant cells. The MOST likelycausative agent is:

（A）Coxsackievirus

（B）Orf virus

（C）Herpes simplex virus type 1

（D）Varicella-zoster virus

正解：D 解答を投票する

ABMM 無料問題集「American Society of Microbiology ABMM」

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